phonePLENVU® Hotline 1-855-697-5368
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When did your doctor tell you to take your first dose?
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Select a dosing option
(More commonly prescribed)

When taking PLENVU®, remember...

Stay hydrated
It’s important that you drink clear liquids before, during, and after your prep
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PLENVU® can be refrigerated
Use within 24 hours after it’s mixed with water
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Stay near a bathroom
Your first bowel movement will likely happen 1 to 2 hours after your first dose of PLENVU®
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Avoid certain beverages
These include alcohol, milk, red- or purple-colored liquids, or drinks containing pulp
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Create your PLENVU® dosing schedule

Use the tool below to set your dosing schedule. Always follow the instructions given to you by your doctor for taking PLENVU®.

1. Day of colonoscopy

2. Time of colonoscopy

Select the schedule prescribed by your healthcare provider. If you are unsure, please call your healthcare provider’s office.

Same-Day
Morning-of-Colonoscopy

OR

2-Day Split-Dosing

Time of appointment:

Optional: NPO

hours prior to colonoscopy
Calculate

3. Results

Dose 1:
--

Dose 2:
--

Stop drinking liquids at:
--

Time and day of colonoscopy:
--

Send

OR

Print
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Call the toll-free PLENVU®  hotline for assistance
hotline
1-855-697-5368
Multilingual assistance available.
(Over 200 languages supported)
call
PLENVU® Texting Program
text
for text message reminders, helpful tips, and more.*
Text PLENVU to 84883
for text message reminders,
helpful tips, and more.*
*At no cost with an unlimited texting plan; otherwise, message and data rates may apply. Message frequency determined by user. Text HELP to 84883 for help. Text STOP to 84883 to cancel. For terms, visit cs1.me/plenvu
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INDICATION

PLENVU® (polyethylene glycol 3350, sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride, and potassium chloride
for oral solution) is a prescription medication used by adults to clean the colon before a colonoscopy.

IMPORTANT SAFETY INFORMATION

  • Do not take PLENVU® if you have a blockage in your intestine (bowel obstruction), an opening in the wall of your stomach or intestine (bowel perforation), problems with food or fluid emptying from your stomach (gastric retention), a problem with food moving too

INDICATION

PLENVU® (polyethylene glycol 3350, sodium ascorbate, sodium sulfate, ascorbic acid, sodium chloride, and potassium chloride for oral solution) is a prescription medication used by adults to clean the colon before a colonoscopy.

IMPORTANT SAFETY INFORMATION

  • Do not take PLENVU® if you have a blockage in your intestine (bowel obstruction), an opening in the wall of your stomach or intestine (bowel perforation), problems with food or fluid emptying from your stomach (gastric retention), a problem with food moving too slowly through your intestines (ileus), a very dilated large intestine, or an allergy to any of the ingredients in PLENVU®.
  • It is important to drink sufficient clear liquids before, during, and after the use of PLENVU®. Be sure to consume additional clear liquids after the first dose and second dose of PLENVU®. Stop drinking liquids 2 hours prior to colonoscopy.
  • Before you take PLENVU®, talk to your doctor if you:
    • Have problems with serious loss of body fluid (dehydration) and changes in blood salts (electrolytes).
    • Have heart problems or take medication that affects your heart. Your doctor may consider obtaining an electrocardiogram (ECG) test if you are at an increased risk for heart rhythm abnormalities.
    • Have a history of seizures or take antiseizure medication.
    • Have kidney problems or take medication that affects kidney function. Your doctor may want to perform blood testing before and after your colonoscopy.
    • Have a history of stomach or bowel problems, such as ulcerative colitis, a bowel blockage, or a suspected opening in the wall of your stomach or intestine.
    • Have problems swallowing, heartburn (gastric reflux), or if you inhale food or fluid into your lungs when eating or drinking (aspirate).
    • Have a condition that destroys red blood cells, called glucose-6-phosphate dehydrogenase (G6PD) deficiency.
    • Are withdrawing from drinking alcohol.
    • Have phenylketonuria (PKU). PLENVU® contains aspartame equivalent to 491 mg of phenylalanine per treatment.
    • Are pregnant or plan to become pregnant.
    • Are breastfeeding or plan to breastfeed.
  • PLENVU® may affect how other medications work. Tell your doctor about all other medications (including prescription and nonprescription medicines, vitamins, and herbal supplements) you take before you take PLENVU®.
  • Do not take oral medications within 1 hour before or after starting each dose of PLENVU®. Do not take other laxatives while taking PLENVU® and do not take PLENVU® with starch based thickeners.
  • Symptoms of serious allergic reactions may include skin rash, itching, raised red patches on your skin (hives), swelling of the face, lips, tongue, and throat, and kidney problems.
  • In clinical studies with PLENVU®, the most common side effects in patients taking PLENVU® were nausea, vomiting, dehydration, and abdominal pain/discomfort.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
For product information, adverse event reports, and product complaint reports, please contact:
Salix Product Information Call Center
Phone: 1-800-321-4576
Fax: 1-510-595-8183
Email: salixmc@dlss.com
Please click here for full Prescribing Information, including Medication Guide and Instructions for Use.